News

Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


Projects and Collaborations

Collaborations

Strangi & Steinmetz groups (CWRU) are collaborating on the research project: "Plasmonics goes Viral"

Strangi Group and CNR Nanotec (Italy) are developing a new class of metamaterials for biosensing and plexcitonics.

Strangi group and De Angelis group (IIT) are designing and fabricating hypersensitive biosensors based on Hyperbolic Metamaterials

Recent Publications: (see publications List)

Our most recent work “Extreme sensitivity biosensing platform based on hyperbolic metamaterials” just came out on NATURE MATERIALS (2016) doi:10.1038/nmat4609
http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat4609.html

Our recent studies on Hyperbolic Metamaterials have been published on Scientific Reports (Nature Publishing)

- “Large spontaneous emission rate enhancement in grating coupled hyperbolic metamaterials”, SCIENTIFIC REPORTS (NATURE) 4, 6340 (2014)

- "Dielectric singularity in HMM: the inversion point of coexisting anisotropies" SCIENTIFIC REPORTS (NATURE) 6, 20002 (2016)


Next Conferences and Meetings.....see the section at the bottom

Conferences, meetings and workshops organized by NANOPLASM

NANOPLASM 2018 the international conference on "Frontiers in Plasmonics and Nano-Optics” chaired by Prof. Strangi will be held in Cetraro (Italy) June 10-15, 2018
http://nanoplasmconference.com

The Scientific Initiative "From Life to Life" by G. Strangi and R. Bartolino is promoted by the Accademia Nazionale dei Lincei (Rome, Italy).
The first volume of the scientific initiative has been published by Springer - Rendiconti Lincei Volume 26, Supplement 2 - August 2015

Prof. Strangi will give an invited Talk at Metamaterials 2018, August 2018 (Espoo, Finland).

Prof. G. Strangi will be one of the keynote speakers at EMP2018 (Montreal, Canada) July 2018 http://emp2018.inrs.ca

Prof. Strangi has been nominated President of the Scientific Committee of The Foundation "Con Il Cuore" - Italy

NEWS:

Welcome to Sharmistha Chatterjee. She joined our group to investigate new plasmonic nanostructures for advanced optical sensing.

Congratulations to Mohamed El Kabbash on a successful PhD defense, and his new job at Rochester University!


We are seeking strongly motivated graduate and undergraduate students to investigate the fascinating world of plasmonic metamaterials.


HomeResearchHyperbolic Metamaterials: Advanced Biosensing and Imaging

Hyperbolic Metamaterials: Advanced Biosensing and Imaging

More than 1.5 million new cancer diagnoses are expected in 2016, imm1and more than half a million Americans die from cancer every year. Increased awareness, high-throughput screening, and detailed medical databases have increased our understanding of cancer and made detection and treatment more effective. Advanced diagnostics will play a critical role in making continued progress on survival rates and quality of life. Ultrasensitive devices that can detect low-concentration biomarkers can identify the onset of cancers before they become clinically relevant.  Such biosensors can also be used to track every aspect of the treatment regimen, from the progress of the disease to the effectiveness of clinical interventions, such as immunotherapies.

imm2This project aims to develop a novel plasmonic biosensor platform that will outperform standard detection techniques, including enzyme-linked immunosorbent assay (ELISA) in both sensitivity and read-out time.   It combines two revolutionary technologies:  hyperbolic metamaterials (HMMs) with their ultrasensitive plasmon modes, and aptamers as high-specificity, high-affinity recognition molecules that can be custom designed for a wide variety of possible biomarkers.  The great potential of HMMs has been dramatically illustrated in our preliminary experiments, recently published in Nature Materialsimm3By optically coupling the HMM to an avidin-functionalized diffraction grating within a microfluidic chip, we were able to achieve a device with a record sensitivity, and the lowest detection limit for the small-molecule analyte biotin (2.4 pg/mL) of all biotin assay techniques developed to date. Our proposal seeks to significantly broaden the scope and practicality of this sensing platform, making it a universal, customizable system by using aptamers as the bio-recognition element.

 

 

 

 

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References:  (Among others see Publication list)

  • (2016) Nature Materials, 15, 621-627, “Extreme sensitivity biosensing platform based on hyperbolic metamaterials
  • (2016) Adv. Opt. Mat., 4, 11, ‘Enhancing the Angular Sensitivity of Plasmonic Sensors Using Hyperbolic Metamaterials’
  • (2017) EPJ-AM, 4,1, “Hyperbolic metamaterials-based plasmonic biosensor for fluid biopsy with single molecule sensitivity”

International Conferences and Meetings

Nanoplasm 2018 - Frontiers in Plasmonics and Nanophotonics

Nanoplasm 2018 - Frontiers in Plasmonics and Nanophotonics

International Conference on Plasmonics and Nanophotonics Cetraro (CS) - Italy - 10 - 15 June...

Metamaterials' 2018 - Espoo (Finland) 27-31 August 2018

Metamaterials' 2018 - Espoo (Finland) 27-31 August 2018

Aalto University (Espoo, Finland)The 12th International Congress on Artificial Materials for...

EMP18 - Montréal (Québec)

EMP18 - Montréal (Québec)

International COnference on Energy, Materials and Photonics Montréal 8 - 11 July...

  • Nanoplasm 2018 - Frontiers in Plasmonics and Nanophotonics

    Nanoplasm 2018 - Frontiers in Plasmonics and Nanophotonics

  • Metamaterials' 2018 - Espoo (Finland) 27-31 August 2018

    Metamaterials' 2018 - Espoo (Finland) 27-31 August 2018

  • EMP18 - Montréal (Québec)

    EMP18 - Montréal (Québec)

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